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个人简介
Dr. Gelber developed the Q-TWiST method (Quality-adjusted Time Without Symptoms of disease and Toxicity of treatment) for incorporating quality-of-life considerations into treatment comparisons. This quality-adjusted survival technique provides a framework to balance the benefits of disease control against the costs of treatment side effects using threshold utility analysis and patient preferences. He also created the STEPP method (Subpopulation Treatment Effect Pattern Plot) which uses data from randomized clinical trials to graphically illustrate the pattern of differences in treatment effectiveness as a function of a covariate of interest. Dr. Gelber has directed the Statistical Center for the International Breast Cancer Study Group (IBCSG) since 1978. This consortium of institutions conducts Phase III clinical trials for adjuvant therapy for breast cancer. In addition, he is the senior biostatistician for two three major studies of adjuvant treatment for HER2-positive breast cancer conducted by the Breast International Group (BIG: the HERA and, ALTTO and APHINITY trials).
研究兴趣
论文共 487 篇作者统计合作学者相似作者
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Isabella Sala,Eleonora Pagan,Laura Pala,Chiara Oriecuia, Marco Musca,Claudia Specchia,Tommaso De Pas, Javier Cortes, Giuseppe Giaccone,Michael Postow,Richard D. Gelber,Vincenzo Bagnardi,
Michail Ignatiadis, Andrew Bailey,Heather McArthur,Sarra El-Abed,Evandro de Azambuja, Otto Metzger, Steve Chui, Max Dieterich, Thomas Perretti,Guenther Steger,Jacek Jassem,Soo Chin Lee,
Cancer Researchno. 9_Supplement (2024): GS01-03
Breast Cancer Research and Treatmentno. 2 (2024): 1-1
CLINICAL CANCER RESEARCHno. 6 (2024): 1093-1103
Cancer Researchno. 9_Supplement (2024): GS02-11
Laura Pala,Eleonora Pagan, Isabella Sala,Chiara Oriecuia, Matteo Oliari, Tommaso De Pas,Claudia Specchia, Emilia Cocorocchio,Emma Zattarin, Giovanna Rossi, Chiara Catania, Giovanni Luca Ceresoli,
EClinicalMedicine (2024): 102681-102681
JCO precision oncologyno. 8 (2024): e2200667-e2200667
Journal of clinical oncology : official journal of the American Society of Clinical Oncologyno. 11 (2024): 1288-1300
Journal of clinical oncology : official journal of the American Society of Clinical Oncologypp.JCO2302292-JCO2302292, (2024)
crossref(2023)
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