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Bio
Dr. Murphy has received research grants from the National Institutes of Health, the National Science Foundation, the American Cancer Society, the American Heart Association, the Arthritis Foundation, and the Rockefeller Brothers Fund. He has co-edited two books and three special journal issues on cell imaging, and has published over 230 research papers and has an h-index of 60.
Dr. Murphy’s career has centered on combining fluorescence-based cell measurement methods with quantitative and computational methods. His group at Carnegie Mellon did extensive work on the application of flow cytometry to analyze endocytic membrane traffic beginning in the early 1980’s. This work included the first (1) measurements of kinetics of rapid acidification of endocytosed material in early endosomes, (2) measurements of the kinetics of exposure of endocytosed material to hydrolytic enzymes in early endosomes in living cells, (3) demonstration in living cells of the regulation of early endosomal pH by the sodium, potassium ATPase, and (4) analysis and isolation of endocytic compartments by flow cytometry and sorting.
Dr. Murphy’s career has centered on combining fluorescence-based cell measurement methods with quantitative and computational methods. His group at Carnegie Mellon did extensive work on the application of flow cytometry to analyze endocytic membrane traffic beginning in the early 1980’s. This work included the first (1) measurements of kinetics of rapid acidification of endocytosed material in early endosomes, (2) measurements of the kinetics of exposure of endocytosed material to hydrolytic enzymes in early endosomes in living cells, (3) demonstration in living cells of the regulation of early endosomal pH by the sodium, potassium ATPase, and (4) analysis and isolation of endocytic compartments by flow cytometry and sorting.
Research Interests
Papers共 421 篇Author StatisticsCo-AuthorSimilar Experts
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bioRxiv the preprint server for biology (2024)
Molecular biology of the cellpp.mbcE24020095-mbcE24020095, (2024)
BIOINFORMATICSno. 2 (2024)
Methods in molecular biology (Clifton, N.J.) (2024): 231-244
crossref(2023)
biorxiv(2023)
Jiahe Lu, Alisa Veler,Boris Simonetti,Timsse Raj, Po Han Chou,Stephen J. Cross,Alexander M. Phillips,Xiongtao Ruan,Lan Huynh,Andrew W. Dowsey,Dingwei Ye,Robert F. Murphy,
bioRxiv (Cold Spring Harbor Laboratory) (2023)
CANCER RESEARCHno. 7 (2023)
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