基本信息
浏览量:1
职业迁徙
个人简介
My laboratory at the University of Arizona is involved with studies of the molecular biology and signaling mechanisms of the prostanoid receptors, another subfamily of the GPCRs. Prostanoid receptors mediate the actions of the prostaglandins, which are hormonal substances that are involved with pain, fever and inflammation. Our studies of the prostanoid receptors led to the first cloning of the human EP2 receptor and to the cloning of the EP3 and FP receptor alternative splice variants. We have also characterized the activation of novel signaling pathways by these receptors involving phosphatidylinositol 3-kinase and elements of the Wnt signaling pathway. These findings have significance towards our understanding of cancer and other diseases.
研究兴趣
论文共 189 篇作者统计合作学者相似作者
按年份排序按引用量排序主题筛选期刊级别筛选合作者筛选合作机构筛选
时间
引用量
主题
期刊级别
合作者
合作机构
Akito Onishi, Akiko Higashiyama, Shunya Yanagawa,Naofumi Seira,John W Regan,Kento Ohkawachi,Masaya Denda,Keijo Fukushima,Akira Otaka,Hiromichi Fujino
Proceedings for Annual Meeting of The Japanese Pharmacological Societyno. 0 (2022)
Proceedings for Annual Meeting of The Japanese Pharmacological Societyno. 0 (2022)
Proceedings for Annual Meeting of The Japanese Pharmacological Societyno. 0 (2020)
European journal of pharmacology (2019): 308-315
Pharmacology Research & Perspectivesno. 6 (2018)
加载更多
作者统计
合作学者
合作机构
D-Core
- 合作者
- 学生
- 导师
数据免责声明
页面数据均来自互联网公开来源、合作出版商和通过AI技术自动分析结果,我们不对页面数据的有效性、准确性、正确性、可靠性、完整性和及时性做出任何承诺和保证。若有疑问,可以通过电子邮件方式联系我们:report@aminer.cn