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Bio
Dr. Alvarez is a Professor in the Division of Gynecologic Oncology. He has become a leading expert in the field of clinical gene therapy as it relates to gynecologic malignancy. He has particular expertise in the development of clinical trials in gene therapy. He has begun patient accrual for a phase I trial of an anti-erbB-2 sFv in patients with recurrent ovarian cancer, and is awaiting FDA approval to initiate a second trial using an HSV-TK gene therapy strategy. In addition to gene therapy, Dr. Alvarez's experience includes clinical trials in the area of chemotherapy, radioimmunotherapy, chemoprevention, and co-operative group trials for gynecologic malignancies. Dr. Alvarez’ grant support for which he serves as a PI include: Gynecologic Oncology Group (NIH, 3010 CA 12484-1751, $108,484 ); Intracellular Single-Chain Antibody Gene Therapy for Ovarian Cancer (NCI, PA-94-050, $200,000); Phase II Trial of 9 Cis Retinoic Acid in Patients with Cervical Intraepithelial Neoplasia (NCI, N01-CN-65024-32, $495,255); and, Molecular Chemotherapy for Ovarian Cancer (NCI, PAR-95-023, $200,000). Additionally, Dr. Alvarez serves as co-investigator on NIH funded studies such as: Prevention and Control of STD Related Morbidity (NIH, A1-94-16, $5,239,421); Randomized Trial on the Clinical Management of ASCUS and LGSIL of the Cervix (NCI, N01-CN-55154, $4,384,939); Gene Therapy for Ovarian Cancer (NCI, PA94-086, $941,476); sFv Mediated Oncogene Knockout for Chemosensitization (NCI, 1 R01 CA72532-01A1, $825,277); and, Cancer Gene Therapy Training Program (NIH, $154,565). Dr. Alvarez directs the Women's Cancer Program of the UAB Comprehensive Cancer Center and has mentored many fellows in Gynecologic Oncology. His success as a mentor is evidenced by the many young investigators that have completed the gynecologic oncology fellowship and pursued academic careers. Fellows that he has mentored include (current locations) Drs. Mack Barnes (UAB), Wendel Naumann (Carolinas Medical Center), Maria Bell (Louisiana State University), Matt Robertson (UAB), and Tim Vanderkwaak (UAB).
Research Interests
Papers共 496 篇Author StatisticsCo-AuthorSimilar Experts
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Jessica P. Miller,Ryan G. Morrison, Emily Mechling, Karen Tisdale,Katherine Frederick-Dyer,Brannan B. Griffin,Ben H. Park,Lauren S. Prescott,Marta A. Crispens,Ronald Alvarez,Arthur Fleischer
WFUMB Ultrasound Openno. 1 (2024): 100031
CANCER MEDICINEno. 3 (2024): e6812-e6812
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Author Statistics
#Papers: 502
#Citation: 19938
H-Index: 76
G-Index: 123
Sociability: 7
Diversity: 3
Activity: 22
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