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Bio
His lab at Monash employs a range of biophysical approaches, including NMR, SPR, ITC and X-ray crystallography, as well as molecular modelling and design, in studies of peptides and proteins from venomous organisms. One of the venom-derived peptides he works with has completed Phase 1 clinical trial for autoimmune diseases and another is the basis for development of ultra-rapid acting insulins that are currently undergoing preclinical evaluation. He is also designing small cyclic peptides that show promise as anti-infective agents with a novel mechanism of action. In addition, his lab applies a combination of structure-based and fragment-based drug discovery programs to protein targets in the areas of infectious and parasitic diseases, graft rejection and metabolic diseases. Ray Norton has published over 380 articles, received numerous national awards, and is an inventor on more than 10 patents. His h-factor is 67 and his papers have been cited > 17,400 times (Google Scholar). He leads a group of more than 15 researchers and has been successful in attracting funding from NHMRC, ARC, Wellcome, Diabetes Australia and NIH. He was recently elected a Fellow of the International Society of Magnetic Resonance. He is Chair of the Council of the International Conference on Magnetic Resonance in Biological Systems (ICMRBS) and a member of the Council of the International Society on Toxinology.
Research Interests
Papers共 603 篇Author StatisticsCo-AuthorSimilar Experts
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BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICSno. 1 (2024): 140952-140952
Karoline Sanches,Lauren M. Ashwood, Abisola Ave-Maria Olushola-Siedoks,Dorothy C. C. Wai,Arfatur Rahman,Kashmala Shakeel,Muhammad Umair Naseem,Gyorgy Panyi,Peter J. Prentis,Raymond S. Norton
PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICSno. 2 (2024): 192-205
Genome biology and evolution (2024)
Michelle Q Phan, Indu R Chandrashekaran, Naureen Akhtar, Evgenia Konstantinidou, Shane M Devine,Bradley C Doak, Thomas Nebl, Darren J Creek, Martin J Scanlon,Raymond S Norton
ACS medicinal chemistry lettersno. 7 (2024): 1071-1079
J. Chem. Inf. Model.no. 10 (2023): 3043-3053
Toxinsno. 3 (2023)
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