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个人简介
I was awarded the PhD in Biology with the study of the molecular mechanisms involved in the evolution of a genetic code alteration (Silva et al., 2007). As a Research Associate in the Population Genetics group at IPATIMUP, I became interested in the evolution of proteins and metabolic pathways, in particular, the dynamics of the NAD metabolic network and its roles in health and disease. These enzymes have been implicated in aging, infection and disease, and are the targets of a novel class of antitumor drugs (Duarte-Pereira et al., 2016).
I am also involved in the development of bioinformatics tools to detect genome rearrangements and pathogen signatures, with implications for diagnosis and therapeutics (Silva et al., 2015). Additional lines of investigation are maintained in collaboration, to address the mechanisms of anti-fungal resistance in clinical isolates (Ricardo et al., 2020), and to predict the impact of human mutations (Cardoso et al., 2019).
研究兴趣
论文共 108 篇作者统计合作学者相似作者
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Foods (Basel, Switzerland)no. 11 (2024): 1759
Diogo Fernandes da Rocha, Marcia Baixia,Ana Grangeia,Raquel Silva,Sergio Castedo,Ana Sofia Correia,Pedro Louro
EUROPEAN JOURNAL OF HUMAN GENETICS (2024): 147-147
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Life Sciences (2023): 121814-121814
JOURNAL OF CLEANER PRODUCTION (2023): 139697-139697
BIOGERONTOLOGYno. 4 (2023): 555-562
Ana Grangeia, Marcia Baixia, Sofia Granja Da Silva,Susana Guimaraes,Carla Ramalho,Raquel Silva,Sergio Castedo,Renata Oliveira
EUROPEAN JOURNAL OF HUMAN GENETICS (2023): 413-414
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FEMS microbiology ecologyno. 3 (2023)
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