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个人简介
He graduated in Biological Sciences - Medical emphasis in IBB (Biosciences Institute of Botucatu) - UNESP (Universidade Estadual Paulista Júlio de Mesquita Filho) - Campus Botucatu (2009). He had his master degree in the Biological Sciences with emphasis in Genetics (2012). In 2017, he obtained a co-tutela PhD degree in Biological Sciences with emphasis in Genetics (IBB-UNESP) and in Biotechnology (Facultat de Farmacia, Universitat Barcelona).
From 2007 to 2022, he worked in the Structural Molecular Biology in the Departament of Physics and Biophysics under supervision of Prof. Marcos Fontes, where he works with snake venom purification, x-ray crystallography, docking, molecular dynamics, Small-angle X-ray scattering (SAXS), circular dichroism (CD), dynamic light scattering (DLS). In 2016, he started a collaboration with Dr. Isabel Usón from Barcelona in the development of methods to aid crystallographic structure elucidation. He is the developer of the software SEQUENCE SLIDER applied to phasing and sequence modeling in proteins purified from natural sources. In this last aim, he integrated data from crystallography, cryo electron microscopy, mass spectrometry and phylogenetic analysis. During the last few years, he spent 4 months in Dr. George Sheldrick laboratory in University of Goettingen (Germany), where he learnt to use the SHELX package, and 6 months in Dr. Randy Read laboratory in Cambridge University (United Kingdom), where he improved his knowledge about MR, software PHASER and statistics.
In the second semester of 2022, he lectured "Bioinformatics" and "Biochemistry" in Universidade Federal de Viçosa (UFV)
Currently, he is Senior Post-doctoral researcher of CQMED under the supervision of Dr. Katlin B. Massirer. In this project, he is integrating machine learning to SLIDER methodology and he will apply it to elucidate new snake venom toxins and curate the databank reviewing snake venom phospholipases A2 sequences.
研究兴趣
论文共 49 篇作者统计合作学者相似作者
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Acta crystallographica. Section D, Structural biologyno. Pt 6 (2023): 449-461
ACS Bio & Med Chem Auno. 2 (2023): 201-210
Biochimie (2022): 105-115
Rafael J Borges,Guilherme H M Salvador, Henrique B Campanelli,Daniel C Pimenta,Mario de Oliveira Neto,Isabel Usón,Marcos R M Fontes
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作者统计
#Papers: 50
#Citation: 507
H-Index: 14
G-Index: 22
Sociability: 6
Diversity: 2
Activity: 39
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