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个人简介
Research in the Klevit group is directed towards an understanding of molecular recognition, with an emphasis on protein-protein interactions that play important roles in human disease. We use a variety of structural, biochemical, molecular biological, and biophysical techniques, with a major emphasis on high resolution NMR spectroscopy and mass spectrometry. Furthermore, we collaborate with colleagues focused on functional aspects of the systems we study. Ongoing projects in the group include the following systems: BRCA1, the breast cancer susceptibility protein; protein ubiquitination in general; human small heat shock proteins alpha-B crystallin and HSP27; and PhoQ, a virulence factor in pathogenic bacteria.
研究兴趣
论文共 256 篇作者统计合作学者相似作者
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Lindsey Ulmer, Daniele Canzani,Christopher Woods, Natalie Stone,Maria Janowska,Rachel Klevit,Matthew Bush
crossref(2024)
Cancer Researchno. 9_Supplement (2024): PO4-28
Journal of proteome research (2024)
Samuel R. Witus,Lisa M. Tuttle, Wenjing Li,Alex Zelter, Meiling Wang,Klaiten E. Kermoade,Damien B. Wilburn,Trisha N. Davis,Peter S. Brzovic,Weixing Zhao,Rachel E. Klevit
The EMBO Journal (2023)
Journal of Biological Chemistryno. 3 (2023): 104057-S568
Wenjing Li,Nozomi Tomimatsu,Corey H. Yu,Jae-Hoon Ji,Salvador Alejo,Samuel R. Witus,Dauren Alimbetov, O'Taveon Fitzgerald, Bo Wu, Qijing Wang,Yuxin Huang, Yaqi Gan,
Molecular cellno. 20 (2023): 3679-+
Cell stress & chaperonesno. 6 (2023): 621-629
Cancer Researchno. 7_Supplement (2023): 6096-6096
CANCER RESEARCHno. 7 (2023)
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