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All who are paying attention now appreciate the complexity, connectivity, and interdependence of biological systems wherein a single 30kb piece of single-stranded RNA can have planetary impacts. It is now abundantly clear that all living organisms are connected to each other through hidden microbial networks, and that while these connections are highly localized, microbial meta-populations act globally. Solving the global challenges of infectious disease, antibiotic resistance, and stabilization of healthy microbial ecosystems depends upon understanding the evolutionary dynamics of microbes and co-evolution of microbes and their own infectious elements. The Whitaker Lab studies on the dynamics of microbes and their viruses using a combination of genomics, experimental evolution, modeling, and molecular biology in a diversity of systems to provide a comparative context for discovering foundational rules of infection genomics. We focus on understanding how the physiology and evolution of rapidly changing components of microbial genomes including CRISPR-Cas immunity and genomic islands change microbial interactions in their natural contexts.
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Papers共 102 篇Author StatisticsCo-AuthorSimilar Experts
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MBIOno. 2 (2024): e0309223-e0309223
Laura C. Suttenfield, Zoi Rapti, Jayadevi H. Chandrashekhar, Amelia C. Steinlein, Juan Cristobal Vera,Ted Kim,Rachel J. Whitaker
biorxiv(2024)
Frontiers in Microbiology (2023)
bioRxiv : the preprint server for biology (2023)
Applied and Environmental Microbiologyno. 7 (2023)
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