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个人简介
Research in the Klevit group is directed towards an understanding of molecular recognition, with an emphasis on protein-protein interactions that play important roles in human disease. We use a variety of structural, biochemical, molecular biological, and biophysical techniques, with a major emphasis on high resolution NMR spectroscopy and mass spectrometry. Furthermore, we collaborate with colleagues focused on functional aspects of the systems we study. Ongoing projects in the group include the following systems: BRCA1, the breast cancer susceptibility protein; protein ubiquitination in general; human small heat shock proteins alpha-B crystallin and HSP27; and PhoQ, a virulence factor in pathogenic bacteria.
研究兴趣
论文共 219 篇作者统计合作学者相似作者
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Lindsey Ulmer, Daniele Canzani,Christopher Woods, Natalie Stone,Maria Janowska,Rachel Klevit,Matthew Bush
crossref(2024)
Wenjing Li, Meiling Wang,Nozomi Tomimatsu, Jae-Hoon Ji,Salvador Alejo,Gangadhara R. Sareddy,Sandeep Burma,Rachel Klevit,Weixing Zhao
Cancer Researchno. 9_Supplement (2024): PO4-28
Sebastian M. Richter, Fan Jin, Tobias Ritterhoff,Aleksandra Fergin, Eric Maurer, Andrea Frank,Alex Hajnal,Rachel Klevit,Frauke Gräter, Annette Flotho,Frauke Melchior
crossref(2024)
Stefan M. Richter,Fan Jin, Tobias Ritterhoff,Aleksandra Fergin,Eric Maurer, Andrea Frank,Alex Hajnal,Rachel E Klevit,Frauke Gräter,Annette Flotho,Frauke Melchior
biorxiv(2024)
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Sebastian M. Richter, Fan Jin, Tobias Ritterhoff,Aleksandra Fergin, Eric Maurer, Andrea Frank,Alex Hajnal,Rachel Klevit,Frauke Gräter, Annette Flotho,Frauke Melchior
crossref(2024)
Wenjing Li,Nozomi Tomimatsu,Corey H. Yu,Jae-Hoon Ji,Salvador Alejo,Samuel R. Witus,Dauren Alimbetov, O'Taveon Fitzgerald, Bo Wu, Qijing Wang,Yuxin Huang, Yaqi Gan,
Molecular cellno. 20 (2023): 3679-+
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Journal of Biological Chemistryno. 3 (2023): 104057-S568
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Cell stress & chaperonesno. 6 (2023): 621-629
Cancer Researchno. 7_Supplement (2023): 6096-6096
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