In 2011 I identified the causative mechanisms of type 2 diabetes and showed how these are returned to normal by weight loss. This has led to a series of clinical studies on remission of type 2 diabetes which have also confirmed and extended understanding of the aetiological mechanisms. My role encompasses application of magnetic resonance methodology to clinical medicine, metabolic research in diabetes, clinical outcome research in diabetic pregnancy, prevention of blindness by retinal screening in diabetes, and teaching in diabetes and obstetric medicine.