基本信息
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Bio
I trained in organic chemistry (BSc 2001, University of Applied Sciences Utrecht; PhD 2007 with Prof. Dr Romano Orru and Prof. Dr Marinus Groen, VU University Amsterdam) and chemical biology (postdoc with Prof. Dr Dr Herbert Waldmann at the Max Planck Institute of Molecular Physiology, Dortmund). In 2009, I began my independent research career at Leeds in 2009, as Senior Research Fellow in the School of Chemistry (2009-2015), Lecturer of Cardiovascular Chemistry at the Leeds Institute of Cardiovascular and Metabolic Medicine (School of Medicine; 2015-2019), and since 2019 as Associate Professor of Chemical Biology. My work includes the development of chemical tools to study protein lipidation, calcium signalling and protein-ligand interactions, the elucidation of the mode-of-action of natural and synthetic compounds (including target and binding site identification), and structure-based drug discovery. Current targets my group works on are TRPC calcium channels and the mitochondrial chaperonin HSPD1. I am an active member of the Astbury Centre for Structural Molecular Biology (Astbury), the Multidisciplinary Cardiovascular Research Centre (MCRC), and the RSC Chemical Biology and Bioorganic Group (@RSC_CBBG). I have published >40 papers (>1000 citations; H index 16). I have wide-ranging experience of teaching and PhD supervision in chemistry, biochemistry and medicine, and am a Fellow of the Higher Education Academy.
Research Interests
Papers共 65 篇Author StatisticsCo-AuthorSimilar Experts
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PHYTOCHEMISTRY LETTERS (2024): 24-35
Sophie E. Roberts,Heather L. Martin, Danah Al-Qallaf,Anna A. Tang,Christian Tiede,Thembaninkosi G. Gaule, Albor Dobon-Alonso,Ross Overman, Sachin Shah, Hadrien Peyret,Keith Saunders,Robin Bon,
iScienceno. 8 (2024): 110461-110461
bioRxiv (Cold Spring Harbor Laboratory) (2023)
Sophie E. Roberts,Heather L Martin,Danah Alqallaf,Anna A. Tang,Christian Tiede,Thembaninkosi G. Gaule, Albor Dobon-Alonso, Ross Overmann,Sachin Shah,Keith Saunders,Robin Bon,Iain W. Manfield,
crossref(2023)
Communications biologyno. 1 (2023): 358-358
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie (2023): 115672-115672
The Journal of biological chemistryno. 2 (2022): 101546-101546
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Author Statistics
#Papers: 65
#Citation: 2104
H-Index: 23
G-Index: 45
Sociability: 6
Diversity: 0
Activity: 1
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