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The focus of our laboratory is the identification of signal transduction pathways which control early events in hematopoietic and lymphopoietic development. One class of molecules studied in our laboratory are receptor tyrosine kinases which are highly conserved molecular "switches" involved in developmental processses. In particular, we study the Kit and Flt3 receptor tyrosine kinases which are expressed on early hematopoietic progenitor cells. We have identified novel signalling molecules which regulate the function of each of these receptors and are currently interested in how these pathways participate in differentiation, cell cycle control, and cell survival responses.
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论文共 190 篇作者统计合作学者相似作者
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Tarak Srivastava,Robert E Garola,Jianping Zhou,Varun C Boinpelly,Mohammad H Rezaiekhaligh,Trupti Joshi,Yuexu Jiang, Diba Ebadi, Siddarth Sharma,Christine Sethna, Vincent S Staggs,Ram Sharma,
JCI insightno. 3 (2024)
JOURNAL OF RHEUMATOLOGYno. 7 (2023): 89-90
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Journal of Experimental & Clinical Cancer Researchno. 1 (2023): 1-13
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Yoshinori Matsumoto,Ioannis D Dimitriou,Jose La Rose,Melissa Lim, Susan Camilleri, Napoleon Law,Hibret A Adissu,Jiefei Tong,Michael F Moran,Andrzej Chruscinski,Fang He,Yosuke Asano,
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