Professor Osborne and his team have an exceptional track record in building new methods and tools that are implemented globally to serve Public Health, Healthcare, Digital Health and Policy sectors. These research outputs include measurement tools (e.g., HLQ, eHLQ, heiQ, MAPT, CHAT) that enable improvements in health and community services to reduce health inequalities. A high-impact research output is the Ophelia (Optimising Health Literacy and Access) process applied in many parts of the world, including within WHO National Health Literacy Demonstration Projects (WHO NHLDPs). He developed the Health Literacy Questionnaire (HLQ) which is one of the most widely used health literacy tools in the world. It is being applied in government-sponsored National Health Surveys, clinical trials, multi-national evaluations, and numerous quality improvement initiatives. He also developed the Influenza Intensity and Impact Questionnaire (FluiiQ; www.fluiiq.com) which has been translated to >50 languages and is used in global vaccine and antiviral trials for influenza and influenza-like illnesses, including COVID-19 and Respiratory Syncytial Virus (RSV). He has completed a wide range of assignments for the WHO. He was the health literacy consultant for the Independent High-Level Commission on Non-Communicable Diseases - WG1 (Health Literacy). He is lead author of the upcoming report, WHO Health Literacy Development for the Prevention and Control of Noncommunicable Diseases which has been classified as a Global Public Health Good.