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Bio
We are interested in cell stress regulatory pathways and protein homeostasis (proteostasis) that ensures the stability of the proteome in health and when challenged by cell stress and the expression of metastable, misfolded, and aggregated proteins. Using C. elegans and human iPS cells, we employ genetic, molecular, small molecule, proteomic and genomic methods and systems level analyses to identify changes during aging and age-associated diseases including metabolic diseases, cancer, and neurodegeneration.
Research Interests
Papers共 294 篇Author StatisticsCo-AuthorSimilar Experts
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Akira Kitamura,Ai Fujimoto, Rei Kawashima, Yidan Lyu, Kotetsu Sasaki, Yuta Hamada, Kanami Moriya, Ayumi Kurata, Kazuho Takahashi,Reneé Brielmann,Laura C Bott,Richard I Morimoto,
Communications biologyno. 1 (2024): 743-743
Cell stress & chaperonesno. 4 (2023): 359-360
PROTEIN SCIENCE (2023)
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PROTEIN SCIENCEno. 12 (2023)
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The Proteostasis Consortium, Overall coordination,Suzanne Elsasser,Lisa P. Elia,Richard I. Morimoto,Evan T. Powers, Harvard Medical School group,Suzanne Elsasser,Daniel Finley,University of California, San Francisco and Gladstone Institutes group I,Beatrice Costa, Maher Budron,
biorxiv(2023)
ACS Central Scienceno. 1 (2023): 87-103
biorxiv(2022)
The Proteostasis Consortium, Overall coordination,Suzanne Elsasser,Lisa P. Elia,Richard I. Morimoto,Evan T. Powers, Harvard Medical School group (analysis),Daniel Finley,University of California, San Francisco and Gladstone Institutes group I (chaperones, analysis),Eric Mockler,Leandro Lima,Steve Finkbeiner,
biorxiv(2022)
Nature agingno. 12 (2022): 1191-1206
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