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Bio
Research Interests
Dr. Barrientos is a behavioral neuroscientist researching the role of inflammation on cognitive impairments. Various physiological insults to the body, such as bacterial or viral infections, surgery and unhealthy diet, trigger an inflammatory response in the brain, and often, these responses are adaptive and beneficial. However, when the immune cells of the brain (microglia) are sensitized, as in aging, these same insults produce exaggerated and prolonged inflammatory responses in the brain that are detrimental to long-term memory, and can increase the risk of developing Alzheimer’s disease or other dementias. Dr. Barrientos’ laboratory examines the neuroimmune phenotype of the aging brain and the underlying mechanisms and signaling pathways involved with each of these “everyday” insults.
Dr. Barrientos is a behavioral neuroscientist researching the role of inflammation on cognitive impairments. Various physiological insults to the body, such as bacterial or viral infections, surgery and unhealthy diet, trigger an inflammatory response in the brain, and often, these responses are adaptive and beneficial. However, when the immune cells of the brain (microglia) are sensitized, as in aging, these same insults produce exaggerated and prolonged inflammatory responses in the brain that are detrimental to long-term memory, and can increase the risk of developing Alzheimer’s disease or other dementias. Dr. Barrientos’ laboratory examines the neuroimmune phenotype of the aging brain and the underlying mechanisms and signaling pathways involved with each of these “everyday” insults.
Research Interests
Papers共 112 篇Author StatisticsCo-AuthorSimilar Experts
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Neurobiology of Aging (2024): 22-32
Sabrina E. Mackey-Alfonso,Michael J. Butler, Ashton M. Taylor, Alberto R. Williams-Medina,Stephanie M. Muscat,Hongjun Fu,Ruth M. Barrientos
Brain, Behavior, and Immunity (2024): 56-69
Pouya Mohammadnezhad,Alberto Valdes,Ruth E. Barrientos,Elena Ibanez,Jane Mara Block,Alejandro Cifuentes
FOODSno. 20 (2023): 3879-3879
Brain, behavior, and immunity (2023): 476-477
L. D. Otto-Dobos, J. C. Santos,L. D. Strehle,C. V. Grant, L. A. Simon, B. Oliver,J. P. Godbout,J. F. Sheridan,R. M. Barrientos, E. R. Glasper,L. M. Pyter
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