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个人简介
The goal of our research is to improve our understanding of the genetic basis of blood disorders known as myeloid malignancies, and to use this knowledge to improve therapies for patients with these disorders. Our efforts are focused on the identification and characterization of somatic mutations in hematologic malignancies using candidate gene, genome-wide, and functional approaches, with a specific interest in the role of JAK-STAT signaling in malignant transformation and in the effects of mutations in epigenetic modifiers in myeloproliferative neoplasms (MPNs) and acute myeloid leukemia (AML). As a physician-scientist, I have a specific interest in translating this knowledge back to the clinic, in the preclinical and clinical evaluation of targeted therapies for leukemia patients, and in the development of clinically tractable genomic assays for patients with hematologic malignancies.
研究兴趣
论文共 823 篇作者统计合作学者相似作者
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crossref(2024)
Nature cancerno. 7 (2024): 958-959
Blood Advancesno. 5 (2024): 1137-1142
crossref(2024)
Pamela J. Sung, Murugan Selvam,Simone S. Riedel,Hongbo M. Xie, Katie Bryant,Bryan Manning,Gerald B. Wertheim,Katarzyna Kulej, Lucie Pham,Robert L. Bowman,Jennifer Peresie,Michael J. Nemeth,
Leukemiano. 2 (2024): 291-301
crossref(2024)
Blood advancesno. 5 (2024): 1137-1142
Journal of Clinical Oncologyno. 16_suppl (2024)
Nature cardiovascular researchno. 1 (2024): 60-75
Jessica E. Pritchard,Juliette E. Pearce,Inge A. M. Snoeren,Stijn N. R. Fuchs,Katrin Gotz,Fabian Peisker,Silke Wagner,Adam Benabid, Niklas Lutterbach, Vanessa Kloker,James S. Nagai,Monica T. Hannani,
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作者统计
#Papers: 822
#Citation: 75283
H-Index: 121
G-Index: 268
Sociability: 9
Diversity: 0
Activity: 8
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