Robert W. Hoffman - Immunology, 1Eli Lilly and Company

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LP-195 Design of a Phase 2 Study Evaluating the Efficacy and Safety of Nipocalimab in Adult Patients with Active Systemic Lupus Erythematosus

Fang Liu-walsh,Bart van Hartingsveldt,Qing Zuraw,Robert Hoffman,Terence Rooney,Sheng Gao, YoungJa Lee,Robert Gordon,Jocelyn Leu,Cesar Calderon,Federico Zazzetti,Anne Stevens,George Vratsanos

E-Poster Presentation (2023)

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POS1130 DESIGNING OF A PHASE 2, MULTICENTER, RANDOMIZED, PLACEBO-CONTROLLED, DOUBLE-BLIND STUDY TO ASSESS THE EFFICACY AND SAFETY OF NIPOCALIMAB, AN FCRN INHIBITOR, IN ADULTS WITH PRIMARY SJÖGREN’S SYNDROME

J. Hubbard,K. Campbell,K. Sivils,R. Hoffman, K.H. Lo,J.H. Leu,S. Bowman, S. Liva,Q. Zuraw,A.M. Stevens,L. Ling,K. Karcher,S. Ramchandren, H. Sun,R.H. Scofield,R. Seror,D.J. Wallace

Annals of the Rheumatic Diseases (2023): 892-893

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611 Efficacy and Safety of Nipocalimab in Adult Patients with Active Systemic Lupus Erythematosus: Design of a Phase 2 Study

Fang Liu-Walsh,Bart van Hartingsveldt,Qing Zuraw,Robert W. Hoffman,Terence Rooney,Sheng Gao, Ana Maria Bravo Perdomo,Robert Gordon,Jocelyn H. Leu,Cesar Calderon,Federico Zazzetti,Anne M. Stevens,George Vratsanos

Scientific Abstracts (2023)

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DESIGNING OFA PHASE 2, MULTICENTER, RANDOMIZED, PLACEBO-CONTROLLED, DOUBLE-BLIND STUDY TO ASSESS THE EFFICACY AND SAFETY OF NIPOCALIMAB, AN FCRN INHIBITOR, IN ADULTS WITH PRIMARY SJOGREN'S SYNDROME

J. Hubbard,K. Campbell,K. Sivils,R. Hoffman, K. H. Lo,J. H. Leu,S. Bowman,S. Liva,Q. Zuraw,A. M. Stevens,L. Ling,K. Karcher,S. Ramchandren,H. Sun,R. H. Scofield,R. Seror,D. J. Wallace

ANNALS OF THE RHEUMATIC DISEASES（2023）

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PO.6.137 Design of a Phase 2, Multicenter, Randomized, Placebo-Controlled, Parallel-Group, Double-Blind Study to Assess the Efficacy and Safety of Nipocalimab in Adults with Active Systemic Lupus Erythematosus

T Rooney,R Gordon, G Vratsanos, C Calderon,S Gao,RW Hoffman,F Zazzetti, F Liu-Walsh, B Van Hartingsveldt, Q Zuraw,JH Leu, A Berhanu Debella

Lupus Science and Medicine（2022）

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O4 Baricitinib-induced Changes in STAT-associated Gene Expression in Systemic Lupus Erythematosus

Thomas Dörner,Yoshiya Tanaka,Michelle Petri,Josef S Smolen,Daniel J Wallace,Ernst R Dow,Damiano Fantini,Richard E Higgs,Guilherme Rocha,Brenda Crowe,Robert J Benschop,Nicole L Byers,Maria E Silk,Stephanie de Bono,Robert W Hoffman

Oral presentations（2020）

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OP0045 DELINEATION OF A PROINFLAMMATORY CYTOKINE PROFILE TARGETED BY JAK1/2 INHIBITION USING BARICITINIB IN A PHASE 2 SLE TRIAL

T. Dorner,Y. Tanaka,M. A. Petri,J. S. Smolen,D. Wallace,B. Crowe,E. Dow,R. E. Higgs,G. Rocha,R. Benschop,M. Silk,S. De Bono,R. Hoffman,D. Fantini

Annals of the Rheumatic Diseases（2020）

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Baricitinib-associated Changes in Global Gene Expression During a 24-Week Phase II Clinical Systemic Lupus Erythematosus Trial Implicates a Mechanism of Action Through Multiple Immune-Related Pathways

Thomas Doerner,Yoshiya Tanaka,Michelle A. Petri,Josef S. Smolen,Daniel J. Wallace,Ernst R. Dow,Richard E. Higgs,Guilherme Rocha,Brenda Crowe,Robert J. Benschop,Nicole L. Byers,Maria E. Silk,Stephanie de Bono,Damiano Fantini,Robert W. Hoffman

Lupus Science and Medicineno. 1 (2020)

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199 Baricitinib in Patients with Systemic Lupus Erythematosus: Results from a Phase 2, Randomized, Double-Blind, Placebo-Controlled Study

Daniel J. Wallace,Richard Furie,Yoshiya Tanaka,Kenneth C. Kalunian,Marta Mosca,Michelle Petri,Thomas Dorner,Mario H. Cardiel,Ian N. Bruce,Elisa Gomez,Amy M. DeLozier,Jonathan Janes,Matthew D. Linnik,Stephanie de Bono,Maria E. Silk,Robert W. Hoffman

Abstracts（2019）

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A Bayesian Gene Network Reveals Insight into the JAK-STAT Pathway in Systemic Lupus Erythematosus

Yupeng Li,Richard E. Higgs,Robert W. Hoffman,Ernst R. Dow,Xiong Liu,Michelle Petri,Daniel J. Wallace,Thomas Doerner,Brian J. Eastwood,Bradley B. Miller,Yushi Liu

PLoS ONE（2019）

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