Reginald Birngruber has published more than 350 articles in laser biomedicine and related fields (Hirsch-factorof 41), among them classical papers on laser tissue interaction in laser safety, the first paper on femtosecond laser effects in biological tissue, basic studies on ultra-short laser pulse mechanisms in ocular tissue, the introduction papers on micro-photocoagulation (SRT) and photodynamic therapy in ophthalmology, a comparative paper on mid-infrared laser ablation of corneal tissue, and first studies on laser effects investigated in vivo by OCT. Recently he was co- author of the first study to investigate the alveolar dynamics using 4-dimensional OCT.

Reginald Birngruber has no projects that are solely his, but makes his experience, expertise, and contacts available to many:currently these include basic mechanisms of photo-thermal and photo- ablative tissue effects,structural and functional optical tissue diagnostics and therapy control.