Andrew Quest currently holds a position as Full Professor. Projects in his laboratory have been funded by national (FONDECYT/PIA/FONDAP) and international programs (ICGEB, Wellcome Trust, ICRO, EMBO). He is one of the six principle investigators that founded the Center for Molecular Studies of the Cell (CEMC) in 2002 and was funded by the FONDAP program until 2012. The mission of this Center of excellence with a strong focus on various aspects of cellular signalling was to create an internationally competitive basic research environment in Chile that favored interactions with clinicians.

He is the current Director of CEMC, which continues to pursue similar scientific objectives, foster the training of advanced human resources by providing unique research opportunities for students at all levels (undergraduate, graduate, post-graduate), as well as favorable conditions for the insertion of young academics into the Chilean research system. Additionally, he was director of the Network for Metabolic Stress Signalling (NEMESIS, 2012-2015), a research initiative that evaluated molecular mechanisms underlying the development of chronic diseases in Chile. Finally, he is now principle investigator and scientific director (area cancer) of another FONDAP center called the (Advanced Center for Chronic Diseases) (ACCDiS, 2013-2023) with six investigators that was funded to study mechanisms leading to the development of cardiovascular diseases and cancer.