Dr. Duh's research in endocrine cancer involved oncogenesis, genetic alteration and redifferentiation treatment of thyroid cancer and adrenal tumors. His clinical research involved patients with adrenal diseases (aldosteronoma, pheochromocytoma, Cushing, incidentaloma and adrenal metastasis), and minimally invasive parathyroid and thyroid operations.

Dr. Duh has developed and actively teaches several new techniques for advance laparoscopic surgery. He has authored or co-authored more than 250 articles and textbook chapters on topics of endocrine surgery and laparoscopic surgery. Dr. Duh was the Site Principal Investigator for a multi-center Veterans Affairs Medical Center prospective randomized trail of open mesh versus laparoscopic inguinal hernia repair, the results of which was published in New England Journal of Medicine. He has started the program in robot-assisted laparoscopic general surgery at the VA Medical Center, currently focused on inguinal hernias.