Dr. Zhang has over 15 years of research experience in the field of cancer biology with specific emphasis on identifying novel molecular targets in pancreatic cancer and diffuse intrinsic pontine glioma (DIPG) that are important in the response to radiation and immune checkpoint inhibitors. He is involved with several translational therapeutic projects to optimize the use of agents targeting ATM, PARP, DNA-PK, and FBXW7. Dr. Zhang also has extensive experience in mechanism-based studies of DNA double-strand break repair pathways and protein post-translational modifications. His expertise in laser microirradiation was essential in establishing this platform in the Experimental Irradiation Shared Resource in the UMCCC.