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Bio
His research career started from 2008, focusing on the function of insulin-like growth factor binding protein 2 in study and memory of mouse. Of note, his researches on hepatocellular carcinoma (HCC) began from 2010 and had independently accomplished several projects of National Natural Science Foundation of China with following original findings: (1) Wnt/β-catenin enhances hypoxia-induced epithelial-mesenchymal transition via interaction of β-catenin and hif-1α; (2) an analog of Cantharidin and protein phosphorylase 2A inhibitor sensitizes chemotherapy by promoting drug delivery into cancer environment; (3) myocyte enhancer factor 2C functions in HCC as a double-edged manner; (4) Helicobacter pylori recurrence negatively correlates with human development index; (5) identified a novel subset of tumor-associated macrophage that can promote the progression of HCC and pancreatic cancer. His current interests are mechanisms of cancer metastasis, stem cell-based artificial liver, hypoxic cancer immunology, and development of novel strategies for cancer therapy. In addition, he is also dedicated to clinical research such as vascular resection in hepato-pancreatic-biliary (HPB) surgery, diagnostic modality of HPB cancers, and evaluation of several anti-tumor agents. Furthermore, he is interested in using systematic review and meta-analysis to evaluate promising cancer interventions in diagnosis and treatment.
Research Interests
Papers共 159 篇Author StatisticsCo-AuthorSimilar Experts
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Jun-Kai Ma, Li-Da Su,Lin-Lin Feng, Jing-Lin Li, Li Pan, Qupei Danzeng,Yanwei Li, Tongyao Shang,Xiao-Lin Zhan,Si-Ying Chen,Shibo Ying,Jian-Rao Hu,
Nature communicationsno. 1 (2024): 3976-3976
CANCER LETTERS (2024): 216654-216654
MedScienno. 6 (2024)
Qi Zhang,Junli Wang,Yu Lou, Xiaojun Peng,Mao Ye,Wanyue Cao,Jiangchao Wu, Zhihui Yan, Xiaowen Zhao, Yu Zhou,Chenlei Zheng,Xiaobao Wei,
crossref(2024)
Chenlei Zheng,Junli Wang,Yu Zhou,Yi Duan, Rujia Zheng, Yuting Xie,Xiaobao Wei,Jiangchao Wu,Hang Shen,Mao Ye, Bo Kong,Yun-Hua Liu,
Studies in health technology and informatics (2024): 1579-1583
International Journal of Infectious Diseases (2024): 107003-107003
PANCREASno. 3 (2024): e288-e297
2023 45TH ANNUAL INTERNATIONAL CONFERENCE OF THE IEEE ENGINEERING IN MEDICINE & BIOLOGY SOCIETY, EMBC (2023): 1-4
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