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Bio
The major research thrusts in the Mali laboratory can be categorized as follows: one, development of genome and transcriptome engineering toolsets and their application to systematic genome interpretation and gene therapy applications; and two, study and engineering of gene regulatory networks and cellular niches governing cell fate specification during development utilizing human pluripotent stem cells as the core model system. Given the parallels in phenotypes (such as self-renewal and tumor forming ability) between pluripotent stem cells and cancer cells, a key research thrust is also in dissecting aberrant cellular transformation processes such as during tumorigenesis. As such, the research program lies at the interface of technology development and basic science, and combines core expertise in synthetic biology and regenerative medicine, with instrumentation and materials engineering.
Research Interests
Papers共 144 篇Author StatisticsCo-AuthorSimilar Experts
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Michael M. Allevato, Sally Trinh,Keiichi Koshizuka,Daniela Nachmanson, Thien-Tu C. Nguyen, Yumi Yokoyama,Xingyu Wu,Allen Andres,Zhiyong Wang,Jeramie Watrous,Alfredo A. Molinolo,Prashant Mali,
Cancer Letters (2024): 217089-217089
Dong Jun Park, Wooil Choi, Sakeef Sayeed,Robert A Dorschner,Joseph Rainaldi,Kayla Ho, Jenny Kezios,John P Nolan,Prashant Mali,Todd Costantini,Brian P Eliceiri
Molecular therapy : the journal of the American Society of Gene Therapy (2024)
Timothy Clark, Jillian Mohan,Leah Schaffer,Kirsten Obernier,Sadnan Al Manir, Christopher P Churas,Amir Dailamy, Yesh Doctor,Antoine Forget, Jan Niklas Hansen,Mengzhou Hu, Joanna Lenkiewicz,
bioRxiv : the preprint server for biology (2024)
Shankar Subramaniam, Metin Akay, Mark A. Anastasio, Vasudev Bailey,David Boas, Paolo Bonato,Ashutosh Chilkoti, Jennifer R. Cochran,Vicki Colvin, Tejal A. Desai,James S. Duncan, Frederick H. Epstein,
Kivilcim Ozturk,Rebecca Panwala,Jeanna Sheen,Kyle Ford, Nathan Jayne,Dong-Er Zhang, Stephan Hutter, Torsten Haferlach,Trey Ideker,Prashant Mali,Hannah Carter
Cancer Researchno. 6_Supplement (2024): 4899-4899
Karina Barbosa,Anagha Deshpande, Marlenne Perales,Ping Xiang,Rabi Murad, Akula Bala Pramod,Anna Minkina,Neil Robertson,Fiorella Schischlik,Xue Lei,Younguk Sun,Adam Brown,
BLOODno. 8 (2024): 697-712
Keiichi Koshizuka,Xingyu Wu,Kuniaki Sato, Pham Thuy Vo, Gosia M. Murawska, Tomohiko Ishikawa,Zhiyong Wang,Alfredo A. Molinolo, Edward A. Dennis,Prashant Mali,J. Silvio Gutkind
Cancer Researchno. 6_Supplement (2024): 5996-5996
Yusuke Goto,Keiichi Koshizuka,Toshinori Ando,Hiroki Izumi, Xingyu Wu, Kuniaki Sato, Tomohiko Ishikawa,Kyle Ford,Xiaodong Feng, Zhiyong Wang,Nadia Arang, Michael M Allevato,
Cancer research communications (2024)
Nature Biomedical Engineeringno. 2 (2024): 111-113
crossref(2023)
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