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职业迁徙
个人简介
I was recruited by the CNRS (National Center for Scientific Research). Most past contributions of my group were on virus-cell and host-tumor interactions in Epstein-Barr virus-associated nasopharyngeal carcinomas. We have published over 99 articles in peer-reviewed scientific journals. I am the editor of a book published in 2013 by Landes and Springer « Nasopharyngeal carcinoma: keys for translational medicine and biology » (2013 - ISBN 978-1-4614-5947-1 – more than 8000 chapter downloads between 2013 and 2016).
Currently, our main project is to investigate the immunosuppressive effects of galectin-9, a protein that we first investigated in nasopharyngeal carcinomas but which is also released by tumor or stromal cells in a wide range of human malignancies. Simultaneously, we produce, characterize and develop therapeutic monoclonal antibodies aiming at neutralization of galectin-9 and restoration of anti-tumor immunity (patent W0 2015/185875 A2 licensed to a Biotech company HiFiBiO). We also investigate circulating tumor microRNAs as a source of biomarkers for several human malignancies, including nasopharyngeal and ovarian carcinomas.
I am teaching undergraduate and graduate students at Gustave Roussy and Paris-Saclay University. I am actively involved in NPC Gordon Research Conferences in Hong-Kong (session discussion leader in 2016 and speaker 2018). I am a grant reviewer for several institutions in France, Europe and Hong-Kong. I am academic editor for PLoS One and ad hoc reviewer for about 20 journals.
Currently, our main project is to investigate the immunosuppressive effects of galectin-9, a protein that we first investigated in nasopharyngeal carcinomas but which is also released by tumor or stromal cells in a wide range of human malignancies. Simultaneously, we produce, characterize and develop therapeutic monoclonal antibodies aiming at neutralization of galectin-9 and restoration of anti-tumor immunity (patent W0 2015/185875 A2 licensed to a Biotech company HiFiBiO). We also investigate circulating tumor microRNAs as a source of biomarkers for several human malignancies, including nasopharyngeal and ovarian carcinomas.
I am teaching undergraduate and graduate students at Gustave Roussy and Paris-Saclay University. I am actively involved in NPC Gordon Research Conferences in Hong-Kong (session discussion leader in 2016 and speaker 2018). I am a grant reviewer for several institutions in France, Europe and Hong-Kong. I am academic editor for PLoS One and ad hoc reviewer for about 20 journals.
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