基本信息
浏览量:2
职业迁徙
个人简介
In the developing vertebrate nervous system oligodendrocytes and Schwann cells not only play a vital role in promoting neuron survival, but they also produce the myelin sheath, which is essential for the normal function of the nervous system, a fact underscored by the debilitating consequences of demyelination in multiple sclerosis in the CNS and in peripheral neuropathies of the Charcot-Marie-Tooth (CMT) type.
The discovery of the Periaxin (Prx) gene and its role in forming the Cajal bands (first described by Santiago Ramon y Cajal) in Schwann cells led to the identification of the cause of a severe demyelinating neuropathy-CMT 4F-in humans. This work also permitted the first experimental proof of the proposal by Huxley and Stämpfli (1949) that internodal distance can regulate nerve conduction velocity.
研究兴趣
论文共 122 篇作者统计合作学者相似作者
按年份排序按引用量排序主题筛选期刊级别筛选合作者筛选合作机构筛选
时间
引用量
主题
期刊级别
合作者
合作机构
Routledge eBookspp.197-212, (2023)
引用0浏览0引用
0
0
Journal of the peripheral nervous system : JPNS (2023): S3-S11
引用0浏览0WOS引用
0
0
Sam A Booker, Laura Simões de Oliveira,Natasha J Anstey, Zrinko Kozic,Owen R Dando,Adam D Jackson,Paul S Baxter,Lori L Isom,Diane L Sherman,Giles E Hardingham,Peter J Brophy,David J A Wyllie,
加载更多
作者统计
合作学者
合作机构
D-Core
- 合作者
- 学生
- 导师
数据免责声明
页面数据均来自互联网公开来源、合作出版商和通过AI技术自动分析结果,我们不对页面数据的有效性、准确性、正确性、可靠性、完整性和及时性做出任何承诺和保证。若有疑问,可以通过电子邮件方式联系我们:report@aminer.cn