His research falls broadly in the areas of Artificial Intelligence, Medical Informatics, and Scientometrics and he has published over 130 refereed papers with his work widely cited. His research in Artificial Intelligence has concentrated on the use of decision-theoretic principles to build intelligent systems and he has conducted seminal work in the areas of decision-theoretic planning and probability logic. His current work focuses on intelligent medical training systems and application of AI techniques to surveillance and modeling of vector-borne disease. He currently holds a full professorship in the Faculty of ICT at Mahidol University in Thailand where he is Director of the Mahidol-Bremen Medical Informatics Research Unit and Deputy Dean for Research. He also holds a position as Honorarprofessor for Medical Informatics at the University of Bremen.