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个人简介
My current research interests center on the statistical design and analysis of HIV vaccine efficacy trials, with emphasis on assessing immune correlates of vaccine-induced protection including the "sieve analysis" of the HIV sequences infecting trial volunteers. While being motivated by HIV vaccine efficacy trials, this research contributes to general areas of statistical methods research including surrogate endpoint assessment, causal inference, survival analysis, and efficient randomized trial design. In collaboration with scientists from the Thai Ministry of Health and the United States Military HIV Research Program, Peter led the statistical design and analysis of an immune correlates study of the RV144 "Thai Trial" (published in 2012), which established a process for correlates discovery that may be useful for other vaccine trial settings. In addition, Peter led the statistical design of a sequential Phase 2b trial design for evaluating vaccine efficacy and immune correlates for multiple HIV vaccine regimens (published in 2011), which is planned for implementation and may be useful for other vaccine trial settings. Since 2014 he has also worked in statistical methods and applications in vaccine efficacy trials for other pathogens including malaria, dengue, and rotavirus.
研究兴趣
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Michal Juraska,Angela M Early, Li Li,Stephen F Schaffner,Marc Lievens, Akanksha Khorgade,Brian Simpkins,Nima S Hejazi,David Benkeser, Qi Wang,Laina D Mercer,Samuel Adjei,
The Lancet Infectious Diseases (2024)
medRxiv : the preprint server for health sciences (2024)
Statistical communications in infectious diseasesno. 1 (2024): 20230002-20230002
Pharmaceuticsno. 5 (2024): 594
arxiv(2024)
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Deborah F. King, Helen Groves, Charlie Weller,Ian Jones,Jakob P. Cramer,Peter B. Gilbert,David Goldblatt,Marion F. Gruber,Beate Kampmann,Diadie Maiga, Marcela F. Pasetti,Stanley A. Plotkin,
Anthony Muchai Manyara,Philippa Davies, Derek Stewart,Christopher J Weir, Amber E Young, Jane Blazeby,Nancy J Butcher, Sylwia Bujkiewicz,An-Wen Chan, Dalia Dawoud,Martin Offringa, Mario Ouwens,
BMJ (Clinical research ed.) (2024): e078525-e078525
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