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Our research is directed towards understanding the molecular and biochemical mechanisms resulting in such pathological sequelae, and the environmental and genetic determinants of individual susceptibility. A number of spontaneous and drug-induced diseases are explored in human subjects and in animal models, including liver and neurodegenerative diseases, birth defects, developmental deficits in CNS function and cancer. Relevant genes, proteins/enzymes and molecular target damage are assessed using a combination of chemical, biochemical and molecular biological techniques. To optimize interpretation of the results, in vivo studies are combined with a variety of in vitro approaches, including embryo and cell culture, as well as studies in subcellular fractions and at the molecular level.
Research Interests
Papers共 237 篇Author StatisticsCo-AuthorSimilar Experts
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Danielle M. Drake, Kian Afsharian,Benjamin Or,Aaron M. Shapiro, Michelle L. Lai,Lutfiya Miller,Peter G. Wells
REDOX BIOLOGY (2024): 103070-103070
Danielle M Drake,Danlin Zhen,Isabel Kerrebijn,Benjamin Or, Sophie Gao, Kian Afsharian, Jason Tran,Shama Bhatia, Ashley Cheng,Peter G Wells
Free radical biology & medicine (2023): 272-284
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#Papers: 240
#Citation: 7091
H-Index: 47
G-Index: 77
Sociability: 6
Diversity: 0
Activity: 1
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