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Bio
Dr. Pegine Walrad is a Medical Research Council-funded Senior Lecturer (Associate Professor) in the York Biomedical Research Institute at the University of York (UY) specializing in the functional characterisation of pathogen biology and host:pathogen interactions. Previous work isolated the first trans-regulator of surface antigens in Trypanosoma brucei parasites. Research focuses upon regulators of Leishmania pathogen differentiation to human-infectious forms. Toward this pursuit her lab quantitatively identified the mRNA binding and whole cell proteomes of Leishmania mexicana, identified the RNA binding protein (RBP) targets of the first methylating enzyme implicated in Leishmania virulence, and has quantitatively defined chemotaxis in human-infectious Leishmania. Recent collaborations have isolated a novel RBP master regulator of T.brucei differentiation in the tsetse fly and developed a mathematical model of Leishmania sandfly transmission. She has been awarded three MRC grants, two joint Newton/MRC UK-Brazil Neglected Infectious Diseases grants and participates in two MRC Global Challenges Research Fund consortiums. She has hosted two sandwich PhD students, a Science without Borders fellow and currently mentors two PDRAs, three BBSRC and Departmental PhDs and two MRes students. Pegine leads the Pathogens and Pathogenesis course and lectures for the Advanced Molecular Biology, Immunology and Infection, Microbiology and Neglected Infectious Disease courses at the University of York. She has delivered two invited Parasite Genetics courses in Brazil and has received eight nominations for teaching and supervision awards from student organizations at two prominent universities.
Research Interests
Papers共 29 篇Author StatisticsCo-AuthorSimilar Experts
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Suellen Rodrigues Maran,Krista Fleck, Natalia Melquie Monteiro-Teles,Tony Isebe,Pegine Walrad,Victoria Jeffers,Igor Cestari,Elton J. R. Vasconcelos,Nilmar Moretti
TRENDS IN PARASITOLOGYno. 9 (2021): 815-830
crossref(2021)
N. Baker,C. M. C. Catta-Preta,R. Neish,J. Sadlova, B. Powell, E. V. C. Alves-Ferreira, V. Geoghegan,J. B. T. Carnielli,K. Newling,C. Hughes, B. Vojtkova, J. Anand,
Nidhi S. Dey, Sujai Senaratne,Vijani Somaratne,Nayani P. Madarasinghe, Bimalka Seneviratne, Sarah Forrester, Marcela Montes de Oca,Luiza Campos Reis,Srija Moulik,Pegine B. Walrad,Mitali Chatterjee,Hiro Goto,
JOURNAL OF CLINICAL INVESTIGATIONno. 22 (2021): 1-29
PLOS Neglected Tropical Diseases (2020)
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