Main research activities: research (biochemistry and toxicology), human health risk assessment; DNA-damages in vivo in Human Biomonitoring Studies (DNA-repair); DNA-methylation as an epigenetic biomarker; toxicokinetic models, refinement of human exposure for toxic chemicals, dermal exposure - percutaneous penetration research; human biomonitoring in Czech Republic - mother milk; application of new in vitro genotoxicity testing; application of novel monitoring techniques for atmospheric pollutants; dispersion modeling; health risks of air particles; teaching and supervising of diploma and doctoral Ph.D. students.