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个人简介
Research in the Trainor laboratory focuses on the role of neural crest cells in vertebrate development, evolution and disease. We seek to understand the mechanisms that regulate neural crest cell formation, migration, and differentiation and to apply this basic knowledge to better understand the etiology and pathogenesis of birth defects as well as develop therapeutic avenues for their prevention. We are particularly interested in craniofacial development and currently study neurocristopathies such as Treacher Collins syndrome, Acrofacial Dysostosis - Cincinnati type, cleft lip and palate, and Syngnathia. However we also study the roles of neural crest cells in congenital disorders of the heart and gastrointestinal tract, such as persistent truncus arteriosus and Hirschsprung disease respectively. We use mouse and zebrafish as our primary genetic models, but also utilize chameleons, chickens and lizards in our experimental studies.
研究兴趣
论文共 252 篇作者统计合作学者相似作者
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Ruonan Zhao,Emma L. Moore,Madelaine M Gogol,Jay R. Unruh,Zulin Yu,Allison Scott, Yan Wang, Naresh Kumar Rajendran,Paul A. Trainor
crossref(2024)
Ruonan Zhao,Emma L Moore,Madelaine M Gogol,Jay R Unruh,Zulin Yu,Allison Scott, Yan Wang, Naresh Kumar Rajendran,Paul A Trainor
bioRxiv : the preprint server for biology (2024)
bioRxiv : the preprint server for biology (2024)
Mackenzie A. Michell-Robinson, Kristin E. N. Watt,Vladimir Grouza,Julia Macintosh,Maxime Pinard,Marius Tuznik,Xiaoru Chen,Lama Darbelli,Chia-Lun Wu,Stefanie Perrier,Daryan Chitsaz, Nonthue A. Uccelli,
NEUROLOGYno. 17 (2023)
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Mackenzie Michell-Robinson, Kristin Watt,Vladimir Grouza,Julia Macintosh,Maxime Pinard,Marius Tuznik,Xiaoru Chen,Lama Darbelli,Chia-Lun Wu,Stefanie Perrier,Daryan Chitsaz, Nonthue Uccelli,
Journal of the Neurological Sciences (2023): 121280
Kelly Smallwood, Kristin E N Watt,Satoru Ide, Kristina Baltrunaite,Chad Brunswick,Katherine Inskeep,Corrine Capannari,Margaret P Adam,Amber Begtrup,Debora R Bertola,Laurie Demmer, Erin Demo,
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