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个人简介
Between 1976 and 1982, before the era of interventional cardiology, Professor Serruys established the methodology of quantitative coronary angiography with the bioengineering group within EMC. In 1980 the balloon angioplasty was introduced at the Thorax Centre, and Professor Serruys was scientifically challenged and tried to elucidate the phenomenon of restenosis post angioplasty in a multidisciplinary approach. In those days, Professor Serruys developed his world-wide networks with various experts to unravel the problem of restenosis. After multiple unsuccessful pharmacological trials to control restenosis phenomenon, his scientific focus was shifted to mechanical device engineering such as stenting. In 1986 he introduced this technique in patients in the Netherlands.
Using the latest scientific and experimental knowledge in the field of molecular biology of neointimal inhibition, Professor Serruys and Eduardo Sousa in Brazil introduced the use of drug-eluting stent for the first time in the world, this was in 1999. Professor Serruys revolutionized the field of interventional cardiology by drastically abating the restenosis rate post intervention; however, the implantation of permanent metallic prosthesis was viewed as a major drawback in the treatment of coronary artery stenosis. Therefore in 2006 Professor Serruys introduced worldwide the use of fully biodegradable drug-eluting scaffolds that eliminated the presence of a permanent metallic foreign body in the coronary circulation. In the next decade, Professor Serruys will dedicate his scientific and clinical career to re- revolutionize the field of interventional cardiology by altering the atherosclerotic process and the process through local percutaneous treatment.
研究兴趣
论文共 4203 篇作者统计合作学者相似作者
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JAMA cardiologyno. 5 (2024): 437-448
Ali Aldujeli,Tsung-Ying Tsai,Ayman Haq,Vacis Tatarunas, Aurimas Knokneris,Kasparas Briedis,Ramunas Unikas, Yoshinobu Onuma,Emmanouil S. Brilakis,Patrick W. Serruys
JOURNAL OF THE AMERICAN HEART ASSOCIATIONno. 9 (2024): e033596-e033596
JACC: Cardiovascular Interventionsno. 4 (2024): S47
Marc-André d'Entremont, Denise Tiong,Behnam Sadeghirad, Brian P. McGrath,Giacomo Maria Cioffi, Turki Al Garni, Zain M. Cheema,Jamie Layland,Pruthvi C. Revaiah,Patrick W. Serruys,Gregg W. Stone,Sanjit S. Jolly
The American Journal of Cardiology (2024): 29-39
JOURNAL OF CARDIOVASCULAR COMPUTED TOMOGRAPHYno. 2 (2024): 120-136
Circulationno. 13 (2024): 973-978
Cardiovascular Revascularization Medicine (2024)
Tsung-Ying Tsai,Hesham Elzomor,Hendrik Wienemann,Pruthvi Chenniganahosahalli Revaiah, Ralph Stephan von Bardeleben,Alexander Tamm, Scot Garg,Osama Soliman,Yoshinobu Onuma,Hans R. Figulla,Matti Adam,Tanja Rudolph,
Structural Heartpp.100346, (2024)
Chao Gao, Bin Zhu,Jianzheng Liu,Zhiwei Jiang,Tao Hu,Qiong Wang,Yi Liu,Ming Yuan,Fei Li,Ruining Zhang,Jielai Xia, Yoshinobu Onuma,
BMC Cardiovascular Disordersno. 1 (2024): 1-10
EUROPEAN HEART JOURNALno. 8 (2024): 610-612
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作者统计
#Papers: 4229
#Citation: 229228
H-Index: 206
G-Index: 391
Sociability: 9
Diversity: 3
Activity: 515
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