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Our research has two overarching goals: 1) to understand the role of nuclear The essential B-vitamins folate, vitamin B12 and pyridoxal phosphate function in a metabolic network known as one-carbon metabolism, which is essential for the faithful replication of the genome and maintenance of genome stability. It is also required for the provision of activated methyl groups for cellular methylation reactions. Aberrations in one-carbon metabolism, due to interactions among nutrition and common gene variants, are tightly linked to several common human pathologies. The Stover research group investigates the fundamental chemical, biochemical, genetic and epigenetic mechanisms, and their associated pathways within the one-carbon metabolic network, that underlie the relationships among nutrition, metabolism and risk for birth defects, cancer and neurodegenerative diseases.
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Heidi M Blank, Staci E Hammer, Laurel Boatright, Courtney Roberts, Katarina E Heyden,Aravindh Nagarajan,Mitsuhiro Tsuchiya, Marcel Brun,Charles D Johnson,Patrick J Stover, Raquel Sitcheran,Brian K Kennedy,
bioRxiv : the preprint server for biology (2024)
ANNALS OF NUTRITION AND METABOLISM (2023): 423-423
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JOURNAL OF RAMAN SPECTROSCOPYno. 8 (2023): 806-813
crossref(2023)
CURRENT SCIENCEno. 3 (2023): 331-331
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Annual review of nutritionno. 1 (2023): 1-23
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