iPSC as disease modelling system to understand MDS progression and therapy resistance.
MYBL2 in Breast cancer stem/initiating cells.
Mechanisms regulating proliferation and genomic stability in embryonic stem cells and somatic cells, with a special focus into the role of the transcription factor MybL2 (B-Myb) at the interplay between DNA replication and DNA repair.
Investigation of the molecular basis behind the deletion of chromosome 20q (del20q), and in particular the role of MybL2 haploinsufficiency in the development of haematological diseases.