基本信息
views: 3
Career Trajectory
Bio
Research
An investigation of the effect of H2S on atherosclerosis
We have previously reported that H2S exhibits potent vasodilator and anti-inflammatory activity suggesting that this novel gas may play a part in cardiovascular physiology and pathophysiology. This project seeks to determine whether a deficiency of vasculoprotective H2S may precipitate atherosclerotic disease. Experiments will be carried out in ApoE-/- atherosclerotic mice and combined with investigation of blood vessels obtained from human volunteers collected, after informed consent, during coronary artery surgery. The project centres upon an integrative approach involving studies both in animals and in cell culture.
A study of the biological effects of novel H2S donor drugs
A number of projects are currently under way to determine the biological effects of a range of novel H2S donor agents in inflammation and cardiovascular disease. Possible target for these drugs which are currently being studied include lipopolysaccharide-evoked septic shock and adjuvant-induced knee joint arthritis. A range of techniques including cell culture and associated biochemical and molecular biological characterisation as well as studies in intact animals are ongoing.
Research Interests
Papers共 256 篇Author StatisticsCo-AuthorSimilar Experts
By YearBy Citation主题筛选期刊级别筛选合作者筛选合作机构筛选
时间
引用量
主题
期刊级别
合作者
合作机构
CIRCULATION-ARRHYTHMIA AND ELECTROPHYSIOLOGYno. 3 (2024): e012446-e012446
William Thomas Christopher Procter,James Elliott, Abdul H. Butt,Christopher Monkhouse,Anish N. Bhuva,Philip Moore
PACE-PACING AND CLINICAL ELECTROPHYSIOLOGY (2023)
Antonio Creta, Nicoletta Ventrella,Mark J Earley,Malcolm Finlay,Simon Sporton, Edward Maclean,Vijayabharathy Kanthasamy, Bruna Costa Lemos Silva Di Nubila,Danilo Ricciardi,Vito Calabrese,Francesco Picarelli,Ross J Hunter,
JACC. Clinical electrophysiologyno. 1 (2023): 121-132
Daniel Keene,Nandita Kaza,Ahran Arnold,James P. Howard,Mark Tanner,Paul Foley,Badri Chandrasekaran,Philip Moore, Silvia Bassi,Amal Muthumala, Shouvanik Adhya,Sharad Agarwal,
Heart Rhythmno. 5 (2022): S64-S65
Load More
Author Statistics
#Papers: 258
#Citation: 20250
H-Index: 74
G-Index: 140
Sociability: 6
Diversity: 4
Activity: 8
Co-Author
Co-Institution
D-Core
- 合作者
- 学生
- 导师
Data Disclaimer
The page data are from open Internet sources, cooperative publishers and automatic analysis results through AI technology. We do not make any commitments and guarantees for the validity, accuracy, correctness, reliability, completeness and timeliness of the page data. If you have any questions, please contact us by email: report@aminer.cn