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Our laboratory uses cell biology approaches as well as mouse transgenic and knockout technology to delineate molecular mechanisms underlying the recruitment of leukocytes to sites of inflammation. Our particular interests have included the multi-step cascade of leukocyte recruitment which includes the proteins responsible for catching leukocytes and tethering them to the endothelium, as well as examining the proteins that contribute to leukocyte migration out of the vasculature. A sincere attempt is made to design human systems to test that mechanisms of action uncovered in mice have clinical relevance.
Our laboratory uses cell biology approaches as well as mouse transgenic and knockout technology to delineate molecular mechanisms underlying the recruitment of leukocytes to sites of inflammation. Our particular interests have included the multi-step cascade of leukocyte recruitment which includes the proteins responsible for catching leukocytes and tethering them to the endothelium, as well as examining the proteins that contribute to leukocyte migration out of the vasculature. A sincere attempt is made to design human systems to test that mechanisms of action uncovered in mice have clinical relevance.
Research Interests
Papers共 873 篇Author StatisticsCo-AuthorSimilar Experts
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Erin E Gill,Baofeng Jia,Carmen Lia Murall,Raphaël Poujol,Muhammad Zohaib Anwar, Nithu Sara John, Justin Richardsson, Ashley Hobb,Abayomi S Olabode, Alexandru Lepsa,Ana T Duggan,Andrea D Tyler,
ArXiv (2024)
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Kathleen Margaret Hagen,Paul Gordon,Ariana Frederick,Alexandra Louise Palmer,Pariya Edalat, Yohan Ricci Zonta,Lucas Scott, Melissa Flancia,Jacqueline Kelsey Reid,Matthew Joel,Shalina Sheryl Ousman
NEUROBIOLOGY OF AGING (2024): 1-15
Journal of immunology (Baltimore, Md. : 1950)no. 6 (2024): 1012-1021
biorxiv(2023)
SCIENCEno. 6662 (2023): 1066-+
crossref(2023)
crossref(2023)
crossref(2023)
biorxiv(2023)
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