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个人简介
Infectious diseases such as HIV, hepatitis B and C, affect hundreds of millions of people worldwide. Our group works on the immune response to these infections, focusing on both the host and the pathogen. As there is currently no vaccine to prevent hepatitis C infection, many of our projects have addressed aspects of chronic hepatitis C virus (HCV) infection and vaccine responses. In addition, our group also looks at a range of viruses and bacteria. Overall our main contributions to date have been to define mechanisms of viral persistence, including: T cell escape, antagonism, original antigen sin, integration of non-retroviral RNA viruses; to define the key features of successful immune responses against HCV, leading to trials of a T cell vaccine; and to define the distinctive CD161+ T cell population, which dominates in the human liver.
研究兴趣
论文共 1162 篇作者统计合作学者相似作者
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Journal of Biological Chemistryno. 6 (2024): 107338-107338
Mohammad Ali,Stephanie Longet, Isabel Neale,Patpong Rongkard, Forhad Uddin Hassan Chowdhury,Jennifer Hill,Anthony Brown,Stephen Laidlaw, Tom Tipton,Ashraful Hoque,Nazia Hassan, Carl-Philipp Hackstein,
Natureno. 7993 (2024): 189-194
Nature Communicationsno. 1 (2024)
Nature Communicationsno. 1 (2024): 1-21
Nature Communicationsno. 1 (2024): 1-10
BRAINno. 4 (2024): 1130-1148
Journal of clinical oncology : official journal of the American Society of Clinical Oncologypp.JCO2300934-JCO2300934, (2024)
Antonia Ho, Oliver Galgut,Sian Faustini, Nicholas Peters,Adrian Shields,Paul Klenerman, Susan Hopkins,Victoria Hall, Susanna Dunachie,Alex Richter
Lancet (London, England)no. 10447 (2024): 23-24
The Lancet Rheumatology (2024)
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