His thesis (INSERM, Nice) and post-doctoral training (IRCC, Italy and then INSERM, France) focused mostly on obesity complications, insulin signaling, insulin resistance and receptor tyrosine kinases. Since 2008, his research program focuses on the better understanding of the hepatic complications associated with obesity (Non alcoholic fatty liver disease: NAFLD) and, more recently, with chronic alcohol consumption (alcoholic liver disease, ALD). His translational research mainly focuses on the identification and the study of markers/actors of the progression of NAFLD and ALD.