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Gruss's research has generally covered the topic of control mechanisms in the development of mammals, especially in the development of the nervous system. He has been able to produce insulin using stem cells.
Gruss's work focused on gene regulation processes. He was particularly interested in the genetic and cellular-biological building blocks that switch genetic programmes on and off in tumour viruses and in the course of embryonic development. In experiments on mice, he successfully identified significant controlling genes (known as Pax genes) which regulate the development of various organs. A study of the pancreas which he conducted enabled him to detect genes involved in the development of insulin-producing islets of Langerhans. This also provided the basis for differentiating stem cells in insulin-producing cells.
Gruss's work focused on gene regulation processes. He was particularly interested in the genetic and cellular-biological building blocks that switch genetic programmes on and off in tumour viruses and in the course of embryonic development. In experiments on mice, he successfully identified significant controlling genes (known as Pax genes) which regulate the development of various organs. A study of the pancreas which he conducted enabled him to detect genes involved in the development of insulin-producing islets of Langerhans. This also provided the basis for differentiating stem cells in insulin-producing cells.
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Epstein's Inborn Errors of Developmentpp.772-775, (2016)
Nature Neuroscienceno. 12 (2013): 1906-1906
Strategie, Steuerung und Governance außeruniversitärer Forschungseinrichtungenpp.3-11, (2013)
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