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个人简介
Professor Philippe CLEZARDIN graduated with a PhD in Biochemistry from the University of Lyon, France, in 1983. He completed a postdoctoral training at the Medical Research Council / Scottish National Blood Transfusion Center in Edinburgh (1984-1986). Philippe was then appointed as Research Scientist at INSERM (National Institute for Health and Medical Research) in 1987. He undertook a sabbatical (1990) as visiting scientist at the Ottawa General Hospital (Ottawa, Canada). On returning in Lyon in 1991, he obtained his DSc from the University of Lyon and became Senior Research Scientist at INSERM. He is now Research Director and, since 2011, head of the INSERM Research Unit UMR_S1033 entitled: “Pathophysiology, Diagnosis and Treatments of Bone Diseases” (http://www.lyos.fr) in Lyon, France. Before that he was head of the INSERM Research Unit UMR_S664 entitled: “Mechanisms and Treatments of Bone Metastases” (2005-2010) and Director of the Federative Research Institute “IFR62” entitled: “Cancer, Nutrition and Metabolism” (14 laboratories, circa: 500 people; 2007-2010). Since September 2016, Philippe CLEZARDIN is Professor in Bone Oncology in the Department of Oncology & Metabolism at the School of Medicine, University of Sheffield. He is setting up an International Laboratory between Lyon and Sheffield, which is done under the auspices of INSERM and the Mellanby Bone Centre at the University of Sheffield.
For the past twenty years, Philippe’s main research interest is in the characterisation of molecular mechanisms that drive bone metastasis formation in breast cancer, with the goal of developing anticancer therapies and novel biomarkers for the identification of patients who are at risk of developing bone metastases. He has authored 159 publications with over 6000 citations, and contributed to about 15 chapters in textbooks on cancer research (Google Scholar April 2020, h-index: 53). Philippe is member of the editorial board of the Journal of Bone Oncology (Elsevier). He is Past President of the Cancer and Bone Society. He has been engaged, as academic partner or coordinator, in several European projects within the framework of FP6, FP7 and H2020 research programmes [MetaBre (2004-2007), PROMET (2006-2010), BONE-NET (2011-2014), miROMeS (2016-2017)]. He received a European Star Award (Paris, France, 2015) for the coordination of Marie Curie ITN project BONE-NET.
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