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个人简介
We investigate the mechanisms by which leukocytes, such as T cells, use cell surface receptors, such as the T cell receptor (TCR), to recognise infected or otherwise abnormal cells. They do this by binding to ligands on antigen presenting and target cells. Our focus is on how the structure and binding properties of these receptor/ligand interactions contribute to their function. We apply the insights gained to improve our ability to manipulate immune responses for therapeutic purposes.
研究兴趣
论文共 234 篇作者统计合作学者相似作者
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biorxiv(2024)
Immunotherapy advancesno. 1 (2024): ltae004-ltae004
Ashna Patel,Violaine Andre, Sofia Bustamante Eguiguren,Michael I Barton, Jake Burton,Eleanor M Denham,Johannes Pettmann,Alexander M Mørch,Mikhail A Kutuzov,Jesús A Siller-Farfán,Michael L Dustin,P Anton van der Merwe,
The EMBO Journalno. 1 (2024): 132-150
bioRxiv (Cold Spring Harbor Laboratory)no. 7 (2023): e111841-e111841
Ashna Patel,Violaine Andre, Sofia Bustamante Eguiguren,Michael I. Barton, Jake Burton,Eleanor M. Denham,Johannes Pettmann,Alexander M Mørch,Mikhail A. Kutuzov,Jesús A. Siller-Farfán,Michael L. Dustin,P. Anton van der Merwe,
bioRxiv (Cold Spring Harbor Laboratory) (2023)
Fenglei Li,Sobhan Roy, Jacob Niculcea,Keith Gould,Erin J Adams,P Anton van der Merwe,Kaushik Choudhuri
bioRxiv : the preprint server for biology (2023)
Proceedings of the National Academy of Sciencesno. 2 (2022)
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作者统计
#Papers: 235
#Citation: 17169
H-Index: 69
G-Index: 130
Sociability: 6
Diversity: 3
Activity: 8
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