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Bio
We investigate the mechanisms by which leukocytes, such as T cells, use cell surface receptors, such as the T cell receptor (TCR), to recognise infected or otherwise abnormal cells. They do this by binding to ligands on antigen presenting and target cells. Our focus is on how the structure and binding properties of these receptor/ligand interactions contribute to their function. We apply the insights gained to improve our ability to manipulate immune responses for therapeutic purposes.
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Papers共 224 篇Author StatisticsCo-AuthorSimilar Experts
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biorxiv(2024)
biorxiv(2024)
Ashna Patel,Violaine Andre, Sofia Bustamante Eguiguren,Michael I Barton, Jake Burton,Eleanor M Denham,Johannes Pettmann,Alexander M Mørch,Mikhail A Kutuzov,Jesús A Siller-Farfán,Michael L Dustin,P Anton van der Merwe,
The EMBO Journalno. 1 (2024): 132-150
bioRxiv (Cold Spring Harbor Laboratory)no. 7 (2023)
Ashna Patel,Violaine Andre, Sofia Bustamante Eguiguren,Michael I. Barton, Jake Burton,Eleanor M. Denham,Johannes Pettmann,Alexander M Mørch,Mikhail A. Kutuzov,Jesús A. Siller-Farfán,Michael L. Dustin,P. Anton van der Merwe,
bioRxiv (Cold Spring Harbor Laboratory) (2023)
Fenglei Li,Sobhan Roy, Jacob Niculcea,Keith Gould,Erin J Adams,P Anton van der Merwe,Kaushik Choudhuri
bioRxiv : the preprint server for biology (2023)
The EMBO journalno. 7 (2022): e111841-e111841
Proceedings of the National Academy of Sciencesno. 2 (2022)
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