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Bio
Dr. Owen “Brad” Spiller is a leading international authority on clinical Ureaplasma spp. and Mycoplasma hominis infections. He was the elected Secretary-General for the International Organisation of Mycoplasmology between 2014-2021 and in 2021 he was awarded the Derrick Edward Award for his contribution to the field. He also currently holds honorary positions as consulting microbiology with both Cwm Taf Morgannwg University Health Board and the UK Health Security Agency. Currently his laboratory is the UK antimicrobial sensitivity reference laboratory for all Ureaplasma spp. and M. hominis positive clinical samples submitted to the UK Health Security Agency. In 2014, Brad was additionally appointed adjunct Senior Lecturer (promoted to Associate Professor in 2020) at the University of Western Australia, where he continues to serve as experimental infection advisor to the Large Animal Facility (School of Women’s and Infant’s Health) in Perth. Brad moved from the Department of Child Health to the Department of Medical Microbiology at Cardiff University in 2015, to join Professor Tim Walsh (Head) and Dr. Mark Toleman to form the All Wales Antimicrobial Resistance Research group (@AWARRe Twitter). He has been the Head of Medical Microbiology since July 2020.
The Spiller Laboratory is a research team focussed on determining the underlying mechanisms of antimicrobial resistance (AMR) and pathogenicity in clinical infections, which have expanded from Mollicutes (cell-wall-less bacteria) to include Legionella pneumophila, Streptococcus agalactiae, and E. coli. In 2023, the Spiller laboratory will head the investigation of Gram-positive organisms isolated from neonates in collaboration with the Ineos Oxford Insititute as BARNARDS II is launched across Africa and Asia. The patient groups of interest are pneumonia and sepsis patients (both neonatal and adult) as well as diagnosis and treatment of non-specific urethritis/cervicitis in sexual health patients. These interests include validating new commercial diagnostic assays, developing new antimicrobial agents, developing new high-throughput AST screening platforms and examining suspected pathogenic/virulence genes (this is still the only laboratory that has successfully genetically altered Ureaplasma parvum to date (in collaboration with the Venter Institute). Due to expanding collaborations within AWARRe the Spiller Laboratory also takes an active role in collaborative research on emerging AMR-mediating genes (such as mcr-1, NDM-5, etc) in vitro and in vivo.
Research Interests
Papers共 177 篇Author StatisticsCo-AuthorSimilar Experts
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Elizabeth Agyare,Joseph Elikem Efui Acolatse,Mavis Puopelle Dakorah,George Akafity,Victoria J. Chalker,Owen B. Spiller, Kristan Alexander Schneider, Saviour Yevutsey, Nana Benyin Aidoo, Sophia Blankson, Frederick Mensah-Acheampong,Robert Incoom,
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCESno. 7 (2024)
International Journal of Molecular Sciencesno. 7 (2024): 4000
International Journal of Molecular Sciencesno. 7 (2024): 4000
Frontiers in immunology (2023): 1150208
Antibiotics (Basel, Switzerland)no. 3 (2023): 544-544
Mavis Puopelle Dakorah,Elizabeth Agyare,Joseph Elikem Efui Acolatse,George Akafity,John Stelling,Victoria J. Chalker,Owen B. Spiller, Nana Benyin Aidoo,Frederick Kumi-Ansah, Daniel Azumah, Stephen Laryea,Robert Incoom,
Joseph Elikem Efui Acolatse,Edward A. R. Portal,Ian Boostrom,George Akafity, Mavis Puopelle Dakroah,Victoria J. Chalker,Kirsty Sands,Owen B. Spiller
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