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个人简介
Professor Fiehn’s research aims at understanding metabolism on a comprehensive level in human population cohorts, animal and plant models, and cells and microorganisms. In order to leverage data from these diverse sets of biological systems, his research laboratory focuses on standardizing metabolomic reports and establishing metabolomic databases and libraries, for example the MassBank of North America that hosts over 200,000 public metabolite mass spectra and BinBase, a resource of over 90,000 samples covering more than 1,900 studies. Professor Fiehn’s laboratory members develop and implement new approaches and technologies in analytical chemistry for covering the metabolome, from increasing peak capacity by ion mobility to compound identifications through cheminformatics workflows and software. He collaborates with a range of investigators for interpreting metabolomic data in human diseases through statistics, text mining and pathway-based mapping efforts. He also studies fundamental biochemical questions from metabolite damage repair to the new concept of epimetabolites, the chemical transformation of primary metabolites that gain regulatory functions in cells.
研究兴趣
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HELIYONno. 9 (2024)
Frontiers in immunology (2024): 1345494-1345494
medRxiv : the preprint server for health sciences (2024)
ERJ OPEN RESEARCHno. 2 (2024)
bioRxiv the preprint server for biology (2024)
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