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个人简介
Nuno Dinis Alves PhD at the lab of Prof. Mark Ansorge at the department of the Psychiatry of Columbia University, New York, US.
Nuno is currently interested to understand the contribution of 5-HTergic activity to the important behavioral functions.
During his doctoral studies, he investigated the implication of adult neural plastic mechanisms (e.g., adult-generation of newborn neural cells, synapto-dendritic alterations and epigenetic modifications) for the development, recurrence and treatment of depressive-like symptoms. By establishing an innovative and novel animal model of recurrent depression, I was able to demonstrate that despite an effective recovery of the initial depressive episode, typical antidepressants such as fluoxetine and imipramine can induce either resilience or susceptibility to recurrent depression. Interestingly, these effects are associated to the neurogenic capacity of these drugs.
He is graduated in Biochemistry (2009) by the University of Trás-os-Montes e Alto Douro (UTAD, Vila Real) and Master in Cellular and Molecular Biology (2011) by the University of Coimbra.
研究兴趣
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Lin Y. Hung,Andrew Del Colle,Nuno D. Alves, Yan Tong,Zixing Huang,Sarah Najjar,Narek Israelyan, Melissa Medina, Ray Rahim, Roey Ringel,Michael Gershon,Mark Ansorge,
GASTROENTEROLOGYno. 6 (2023): S412-S413
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eLife (2021)
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