基本信息
浏览量:49
![](https://originalfileserver.aminer.cn/sys/aminer/icon/show-trajectory.png)
个人简介
Spear's research, supported by NIAAA, focuses on two issues: What in brain or environment determine the consequences of alcohol early in life, before and after birth, and how does early experience with alcohol influence later responsiveness to alcohol? They seek to understand (1) what determines alcohol ingestion and reinforcement early in life and how these determinants change as the animal develops from fetus to adulthood, and (2) how early experience with alcohol, prenatal and older, alters this responsiveness. Throughout this analysis they give special attention to the consequences of early learning about the sensory and pharmacological effects of alcohol, and developmental changes in neurochemical systems linked to alcohol ingestion and reinforcement.
A related continuous focus in their laboratory is how the processes of learning and memory change during development from the prenatal period throughout infancy. The central phenomenon in this work has been infantile amnesia, and the theoretical framework for conceptualizing it and related effects emphasizes memory retrieval. Experiments with rats of different ages, from infancy to adulthood, indicate that what is stored in memory changes dramatically with ontogeny and allow the feasibility of interpreting infantile amnesia in terms of an age-specific encoding that results in a failure in later memory retrieval. A related recent focus is in understanding the remarkable strength of memories acquired soon after birth and its relationship to neurochemical and hormonal effects induced by the process of birth.
A related continuous focus in their laboratory is how the processes of learning and memory change during development from the prenatal period throughout infancy. The central phenomenon in this work has been infantile amnesia, and the theoretical framework for conceptualizing it and related effects emphasizes memory retrieval. Experiments with rats of different ages, from infancy to adulthood, indicate that what is stored in memory changes dramatically with ontogeny and allow the feasibility of interpreting infantile amnesia in terms of an age-specific encoding that results in a failure in later memory retrieval. A related recent focus is in understanding the remarkable strength of memories acquired soon after birth and its relationship to neurochemical and hormonal effects induced by the process of birth.
研究兴趣
论文共 409 篇作者统计合作学者相似作者
按年份排序按引用量排序主题筛选期刊级别筛选合作者筛选合作机构筛选
时间
引用量
主题
期刊级别
合作者
合作机构
Denis J O Sullivan,Norman E Spear
Marcela Cullere,Ana Fabiola Macchione,Beatriz Haymal, Martin Paradelo, Marcos Daniel Langer,Norman E Spear,Juan Carlos Molina
加载更多
作者统计
#Papers: 381
#Citation: 10674
H-Index: 51
G-Index: 80
Sociability: 6
Diversity: 0
Activity: 0
合作学者
合作机构
D-Core
- 合作者
- 学生
- 导师
数据免责声明
页面数据均来自互联网公开来源、合作出版商和通过AI技术自动分析结果,我们不对页面数据的有效性、准确性、正确性、可靠性、完整性和及时性做出任何承诺和保证。若有疑问,可以通过电子邮件方式联系我们:report@aminer.cn