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The Drug Design and Development Section (DDDS) is designed to identify drugs that improve brain function and/or forestall the neurodegenerative process in age-related neurodegenerative disorders. Data arising from studies on neurodegenerative and neuroprotective signaling pathways are used to identify potential drug targets. Candidate drugs are first screened for efficacy in cell culture or animal models, and the most effective compounds are moved through preclinical studies to clinical trials. Several drugs that enhance cognitive function are currently in clinical trials, and novel neuroprotective compounds are at various preclinical stages of development.
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论文共 621 篇作者统计合作学者相似作者
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Ageing Research Reviews (2024)
Bioorganic & medicinal chemistry letters (2024): 129885-129885
Yazhou Li,Kelli L Vaughan, Yun Wang,Seong-Jin Yu,Eun-Kyung Bae,Ian A Tamargo,Katherine O Kopp,David Tweedie,Cheng-Chuan Chiang, Keith T Schmidt,Debomoy K Lahiri, Michael A Tones,
GeroSciencepp.1-18, (2024)
Ageing Research Reviewspp.102343, (2024)
Ageing research reviews (2024): 102343-102343
Dilan Athauda,James R Evans, Laura Mahoney-Sanchez,Gurvir S Virdi, Patricia Lopez-Garcia,Anna Wernick,Aaron Wagen,Karishma D’Sa,Joanne Lachica,Stephanie Strohbuecker,Giulia Vecchi,Craig Leighton,
biorxiv(2024)
CELL TRANSPLANTATION (2024)
Vicki Wang,Kuan-Yin Tseng,Tung-Tai Kuo,Eagle Yi-Kung Huang, Kuo-Lun Lan, Zi-Rong Chen,Kuo-Hsing Ma,Nigel H Greig,Jin Jung, Ho-Ii Choi,Lars Olson,Barry J Hoffer,
Journal of biomedical scienceno. 1 (2024): 38-38
Dong Liu, Shih Chang Hsueh,David Tweedie, Nate Price, Elliot Glotfelty,Daniela Lecca,Richard Telljohann,Rafael deCabo, Barry J Hoffer,Nigel H Greig
Brain communicationsno. 4 (2024): fcae204-fcae204
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