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Bio
Nicole Gaudelli studied the structural and mechanistic underpinnings of neocarzinostatin biosynthesis and a non-heme iron oxygenase involved in vancomycin assembly. She studied monocyclic beta-lactam antibiotics and elucidated the mechanism through which they are biosynthesized. She expanded the capabilities of base editing technology by creating the first adenine base editor (ABE) through 7 rounds of directed evolution and engineering.
Dr. Gaudelli is an inventor on numerous base editing patents. Dr. Gaudelli is a recipient of the 2018 American Chemical Society’s “Talented 12” award, recognized as a 2018 STAT News Wunderkind, a 2018 TEDMED Hive honoree, Genetic Engineering and Biotechnology News “Top 10 Under 40 of 2019”, BioSpace’s 2019 “10 Life Science Innovators Under 40 to Watch”, and is MIT’s 2019 Technology Reviews’ 35 Innovators Under 35.
Dr. Gaudelli is an inventor on numerous base editing patents. Dr. Gaudelli is a recipient of the 2018 American Chemical Society’s “Talented 12” award, recognized as a 2018 STAT News Wunderkind, a 2018 TEDMED Hive honoree, Genetic Engineering and Biotechnology News “Top 10 Under 40 of 2019”, BioSpace’s 2019 “10 Life Science Innovators Under 40 to Watch”, and is MIT’s 2019 Technology Reviews’ 35 Innovators Under 35.
Research Interests
Papers共 32 篇Author StatisticsCo-AuthorSimilar Experts
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Nandini Mondal,Alexander Harmon, Elizabeth Budak,Kathy Zhang,Jeffrey Wong, Archita Menon,Adam Wolin, Moriah White,Faith Musenge,Adam Camblin, Cristina Baricordi, Brent Coisman,
MOLECULAR THERAPYno. 4 (2023): 706-707
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Lam, Dieter K.,Feliciano, Patricia R.,Arif, Amena,Bohnuud, Tanggis, Fernandez, Thomas P.,Gehrke, Jason M.,Grayson, Phil, Lee, Kin D.,Ortega, Manuel A., Sawyer, Courtney, Schwaegerle, Noah D.,Peraro, Leila,
Nature Biotechnologyno. 5 (2023): 1-12
Nandini Mondal,Alexander Harmon, Elizabeth Budak, Kathy Zhang, Jeffrey Wong, Conrad Rinaldi,Jenny Olins, Kara Hoar, Archita Venugopal Menon, Moriah White,Faith Musenge, Adam Camblin,
Bloodno. Supplement 1 (2022): 4487-4488
CURRENT OPINION IN STRUCTURAL BIOLOGY (2021): 86-98
bioRxiv (Cold Spring Harbor Laboratory)no. 1 (2020): 1-16
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