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个人简介
Since the early seventies, Nico van Rooijen has been involved in studies on the role of various lymphoid and non-lymphoid cells in the induction of 'in situ' immune reactions against different types of antigen in the spleen. Given the idea that new scientific developments are often preceded by new technology, it was decided to develop new techniques, if answering of the main questions in this research project was hindered by the absence of suitable methodology. So, double radioisotope autoradiography techniques were developed for the simultaneous detection of various lymphoid cells and antigens. A double immuno-enzyme technique was developed that allowed the “in situ” localisation of specific antibody forming cells in combination with their further characterisation. The 'Liposome mediated macrophage suicide approach' has been developed to reveal macrophage functions and is now widely used for studying the many roles of these multifunctional and evolutionary ancient cells.
研究兴趣
论文共 1119 篇作者统计合作学者相似作者
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Janine M. Low-Marchelli,Veronica C. Ardi,Edward A. Vizcarra,Nico van Rooijen, James P. Quigley,Jing Yang
crossref(2023)
Giulia Fulci,Nina Dmitrieva,Davide Gianni, Elisabeth J. Fontana,Xiaogang Pan,Yanhui Lu, Claire S. Kaufman,Balveen Kaur,Sean E. Lawler,Robert J. Lee,Clay B. Marsh,Daniel J. Brat,
crossref(2023)
Toni M. Robinson-Smith, Idit Isaacsohn,Carol A. Mercer,Mingfu Zhou,Nico Van Rooijen,Nader Husseinzadeh, Molly M. McFarland-Mancini,Angela F. Drew
crossref(2023)
Yuru Meng,Michael A. Beckett,Hua Liang,Helena J. Mauceri,Nico van Rooijen, Kenneth S. Cohen,Ralph R. Weichselbaum
crossref(2023)
Toni M. Robinson-Smith, Idit Isaacsohn,Carol A. Mercer,Mingfu Zhou,Nico Van Rooijen,Nader Husseinzadeh, Molly M. McFarland-Mancini,Angela F. Drew
crossref(2023)
Toni M. Robinson-Smith, Idit Isaacsohn,Carol A. Mercer,Mingfu Zhou,Nico Van Rooijen,Nader Husseinzadeh, Molly M. McFarland-Mancini,Angela F. Drew
crossref(2023)
Lorena Hernandez,Tatiana Smirnova,Dmitriy Kedrin, Jeffrey Wyckoff,Liyin Zhu,E. Richard Stanley,Dianne Cox,William J. Muller, Jeffrey W. Pollard,Nico Van Rooijen, Jeffrey E. Segall
crossref(2023)
Janine M. Low-Marchelli,Veronica C. Ardi,Edward A. Vizcarra,Nico van Rooijen, James P. Quigley,Jing Yang
crossref(2023)
Giulia Fulci,Nina Dmitrieva,Davide Gianni, Elisabeth J. Fontana,Xiaogang Pan,Yanhui Lu, Claire S. Kaufman,Balveen Kaur,Sean E. Lawler,Robert J. Lee,Clay B. Marsh,Daniel J. Brat,
crossref(2023)
Janine M. Low-Marchelli,Veronica C. Ardi,Edward A. Vizcarra,Nico van Rooijen, James P. Quigley,Jing Yang
crossref(2023)
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